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Investigating the effect of buspirone in patients with bladder and bowel dysfunction

Investigating the effect of buspirone on irritative and obstructive symptoms in patients with bladder and bowel dysfunction (RCT); A double-blind randomized clinical trial study

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190624043991N28
Enrollment
100
Registered
2024-08-31
Start date
2024-07-25
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with bladder and bowel dysfunction. Neuromuscular dysfunction of bladder, unspecified

Interventions

Intervention 1: Intervention group: the group receiving buspirone with a daily dose of 5 mg, 2 tablets daily. Intervention 2: Control group: control group with placebo (capsule containing sugar that l

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 15 Years

Inclusion criteria

Inclusion criteria: Have bladder and bowel dysfunction Between 6 and 15 years Do not have known problems of mental retardation, learning disorder or known psychiatric problems under treatment Do not have neurological problems Do not have an active urinary tract infection Do not have anatomical problems Be sponsored by the family

Exclusion criteria

Exclusion criteria: Have liver or kidney failure Have diabetes, high blood pressure, or heart abnormalities Take drugs that stimulate the urinary, cardiac, or psychological system Have known intestinal diseases5. Have a history of urinary, cardiac, or neurological surgeries

Design outcomes

Primary

MeasureTime frame
The effectiveness of buspirone as a single drug therapy for patients with urinary or fecal excretion disorders. Timepoint: Two and six months after receiving buspirone treatment. Method of measurement: Questionnaire, Euroflow, electromyography and urinary and intestinal excretion.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Akram Mirzaei

Tehran University of Medical Sciences

mirzaee.scholar@gmail.com+98 21 6634 8560

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026