Antibiotic effect during and after intra-organ stone crushing

Investigating the effect of antibiotics in washing fluid on inflammatory factors during and after transurethral lithotripsy: a single blind clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190624043991N20

Enrollment

Registered

2023-09-25

Start date

2024-02-09

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary tract infection. Urinary tract infection, site not specified

Interventions

Intervention 1: Intervention group: Intervention group: 1000 mg ceftriaxone antibiotic + 6 liters of normal saline 0.9%. they receive. Intervention 2: Control group: control group: normal saline serum

Eligibility

Sex/Gender

All

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Patients in the study and obtaining informed consent aged between 20 and 70 years elective surgery stones smaller than 20 million meters located in the upper lower ureter in CTS without contrast.

Exclusion criteria

Exclusion criteria: Previous history of urinary system surgery Having simultaneous kidney stones Having anatomical or functional kidney disorders Bilateral ureteral stones Positive urine culture before surgery Use of corticosteroids or antibiotics before surgery Immunodeficiency Taking drugs Causes of immunodeficiency Any active or chronic infection during the last three months Diabetes

Design outcomes

Primary

Measure	Time frame
The effect of antibiotics in the lavage fluid on the occurrence of infections during and after intra-organ stone crushing. Timepoint: 6-12 hours after surgery. Method of measurement: Laboratory diagnosis (urine culture and inflammatory markers).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Akram Mirzaei

Tehran University of Medical Sciences

mirzaee.scholar@gmail.com+98 21 6634 8560

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026