Liver Transplantation. Liver transplant status
Conditions
Interventions
Intervention 1: intervention group 1: octerotide 50 mg / h intravenous infusion for three days from one of the Domestic manufacturer factory that will be provided by Namazi Hospital Intervention. Inte
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age between 18 and 60 years 2.Cirrhosis of the liver defined by clinical, biochemical or histological That, properly informed, give their consent to participate in the study and undergo tests and examinations that entails Women of childbearing potential: pregnancy test negative serum or urine, and acceptance of use of adequate contraception since at least 14 days prior to the first dose of study drug until 14 days after the last dose
Exclusion criteria
Exclusion criteria: 1.Pregnant women, nursing mothers, or those who intend to become pregnant during the study period 2.Systolic blood pressure = 150 mmHg and / or diastolic blood pressure = 90 mmHg 3.Previous treatment with transjugular intrahepatic portosystemic shunt (TIPS) or surgical portosystemic shunts 4.Simultaneous Liver, Kidney Transplant 5.Cardiac or respiratory failure 6.Positive for human immunodeficiency virus 7.Urinary retention 8.Ischemic heart disease or peripheral vascular disease 9.Narrow Angle Glaucoma 10.Cerebrovascular occlusions 11.Aortic Aneurysm 12.Thyrotoxicosis 13.Pheochromocytoma 14.Diabetes Melitus 15.History of Hemodialysis prior to Liver Transplant 16.PreTransplant Cr more than 2.5mg/dl
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Glomerular filtration. Timepoint: 3 Days after Intervention, 1week after Intervention, 4 weeks after Intervention. Method of measurement: Change in glomerular filtration rate measured by isotopic tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in renal function. Timepoint: 3days, 1 week, 4 weeks after cessation of treatment. Method of measurement: Lab test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactkamran bagheri lankarani
Shiraz University of Medical Sciences
Outcome results
None listed