Comparison Of the effects of dexmedetomidine and remifentanil on intraoperative hemodynamics and postoperative pain in patients with spine surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190618043934N27

Enrollment

Registered

2024-07-08

Start date

2024-08-22

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spine surgery. Sprain of ligaments of thoracic spine, subsequent encounter

Interventions

Intervention 1: Intervention group: Intervention group 1: The group receiving dexmedetomidine (manufactured by Elixir Pharmaceutical Company, Borujerd - Iran) at a dose of 1 microgram/kg once intraven

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 65 years ASA class I or II candidate for spine surgery Having informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Performing emergency surgery History of previous spine surgery Drug addiction History of neuromuscular, psychiatric, pulmonary, cardiovascular diseases, orthostatic hypotension Any type of brain pathology Previous symptoms of ischemia or stroke Carotid artery and spinal canal stenosis Pregnant women Allergic to the drugs used Lack of control of systemic disease such as high blood pressure, diabetes and significant organ dysfunction of the heart Unpredictable events occurred during the operation such as severe bleeding and surgery lasting more than 3 hours

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: The pain level is evaluated immediately after transfer to the ward, 2, 4, 6 and 8 hours after surgery by the study manager. Method of measurement: Using of Visual Analogue Scale.;Blood pressure: after induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Timepoint: After induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Method of measurement: Using the Saadat monitoring device.;Heart Rate: After induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Timepoint: After induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Method of measurement: Using the Saadat monitoring device.	—

Measure

Time frame

Pain. Timepoint: The pain level is evaluated immediately after transfer to the ward, 2, 4, 6 and 8 hours after surgery by the study manager. Method of measurement: Using of Visual Analogue Scale.;Blood pressure: after induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Timepoint: After induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Method of measurement: Using the Saadat monitoring device.;Heart Rate: After induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Timepoint: After induction of anesthesia, it is evaluated at 20-minute intervals from the time of induction of anesthesia during surgery. Method of measurement: Using the Saadat monitoring device.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNegin Hajati

Birjand University of Medical Sciences

oabstudent@gmail.com+98 56 3238 1500

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026