Multiple sclerosis. Multiple sclerosis
Conditions
Interventions
Intervention 1: Intervention group: Intervention group 1: The receiving group received alpha lipoic acid supplement in the form of 300 mg tablets twice a day (morning and night) for 2 months. Interven
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Relapsing and recovering MS patients with severe disease activity who are treated with rituximab patients with disability grade 4.5 to 6 Patients who are able to walk without assistance Patients who can walk at least 100 meters Age between 20 and 45 years
Exclusion criteria
Exclusion criteria: Unwillingness of patients to cooperate with the research team Absence of more than 3 sessions in practice sessions Not taking alpha lipoic acid medicine regularly Failure to answer the phone call to continue the treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average kinematic parameters of lower limb joints (three-dimensional angles of ankle, knee and thigh joints). Timepoint: At the beginning of the study and before the start of interventions related to each group and 2 months after the relevant interventions, a necessary evaluation is done. Method of measurement: The IMU device is used to check the three-dimensional angles of the ankle, knee and thigh joints.;Average performance variables (7.5 meter walking, standing and timed walking tests). Timepoint: The IMU device is used to check the three-dimensional angles of the ankle, knee and thigh joints. Method of measurement: To evaluate the timed rise and walk test, the time taken for a person to stand up from a normal chair with a seat height of 45 cm (leaning on the back of the chair while the soles of his feet are on the floor and behind the marking line) Get up and walk a distance of three meters at your maximum safe speed and come back and sit back on the chair and lean back. It is recorded by a stopwatch. It is also used to evaluate the 7.5 meter walking test or the 25 foot test, a standard method to check the ability of patients to walk. MS is used by neurologists in such a way that patients are asked to cover a distance of 7.5 meters as quickly as possible, which usually should be done in less than 4 seconds in healthy people and patients who do not have significant mobility disabilities. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZabihullah Mohaqiq
Birjand University of Medical Sciences
Outcome results
None listed