Comparison of onset and duration of pain prescribed by combination of bupivacaine with 5% dextrose and fentanyl with bupivacaine

Comparison of the effect of interautal administration of bupivacaine and dextrose 5% and fentanyl on bupivacaine alone on the onset and duration of analgesia in patients undergoing lower limb orthopedic surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190618043934N2

Enrollment

Registered

2020-04-30

Start date

2020-02-20

Completion date

Unknown

Last updated

2020-05-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of shaft of tibia. Fracture of shaft of tibia

Interventions

Intervention 1: Intervention group: This group under spinal by prescribing marcain 0.5% 1 cc (5 mg) + 25 micrograms fentanyl (cc 0.5) + 0.5 cc of 5% sterile dextrose. Intervention 2: Control group: th

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Having conscious patient satisfaction Patients with ASA class one and two Age between 20 and 50 years No drug addiction No spinal history following surgery in the past week No pregnancy Nhere is no spinal deformity There is no spinal deformity

Exclusion criteria

Exclusion criteria: Patient dissatisfaction to continue studying Duration of surgery over 1 hour Inability to position the patient Spinal Infection Sensitivity to local Anesthetic Drugs High ICP Coagulation Disorders

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 0, 6, 12and 24 hours after surgery. Method of measurement: Using of VAS.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZabihullah Mohaghegh

Birjand University of Medical Sciences

oabstudent@gmail.com+98 56 3232 3232

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026