The effect of Montelukast on the prevention of nasal polyp recurrence

The Effect of Montelukast on Prevention of Nasal Polyps Recurrence Following Functional Endoscopic Sinus Surgery.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190618043934N16

Enrollment

Registered

2023-02-08

Start date

2023-01-21

Completion date

Unknown

Last updated

2023-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic rhinosinusitis. Chronic rhinitis

Interventions

Intervention 1: Intervention group: The first intervention group: Group A received Montelukast tablets 10 mg daily, once at night for 6 weeks. Intervention 2: Intervention group: The second interventi

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Candidate for endoscopic sinus surgery Consent to participate in the study Cooperation with the present research team

Exclusion criteria

Exclusion criteria: History of allergy to prescribed medication for the patient presence of eye disease immunodeficiency disease allergic rhinitis

Design outcomes

Primary

Measure	Time frame
Runny nose. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Headache. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Nasal congestion. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Sinus pain. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Pain around the eyes. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Pus in the nose. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Cough. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Decreased sense of smell Before and After Treatment. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.	—

Measure

Time frame

Runny nose. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Headache. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Nasal congestion. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Sinus pain. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Pain around the eyes. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Pus in the nose. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Cough. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.;Decreased sense of smell Before and After Treatment. Timepoint: Runny nose before and 6 weeks after treatment. Method of measurement: By asking the patient.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactZabihullah Mohaqiq

Birjand University of Medical Sciences

oabstudent@gmail.com+98 56 3232 3232

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026