Effects of propofol and ketofol on transient agitation induced by adenotonsillectomy

Comparison of the effects of ketofol (Ketamine-Propofol mixture) with propofol on Transient agitation in children undergoing Adenotonsillectomy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190618043934N12

Enrollment

Registered

2021-07-11

Start date

2021-04-04

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillitis. Acute tonsillitis

Interventions

Intervention 1: Intervention group 1: The first group in the interventional study are patients who received propofol (made by Fresnius Kabi company in Germany) as a general intravenous anesthetic with

Eligibility

Sex/Gender

All

Age

3 Years to 9 Years

Inclusion criteria

Inclusion criteria: Patients with ASA class one and two Age 3 to 9 years Without any addiction Without any requirements to prescribe any Narcotic drugs in recovery phase Without any known previous propofol allergy reactions

Exclusion criteria

Exclusion criteria: Having mental and behavioral disorders Having a specific illness Cerebral trauma and bleeding or intracerebral mass Having congenital heart disease

Design outcomes

Primary

Measure	Time frame
Agitation. Timepoint: 15, 30 minutes after being in the recovery room and 2, 4 and 6 hours after surgery in the ward. Method of measurement: Using the Modified objective pain score criterion (MOPS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZabihullah Mohaghegh

Birjand University of Medical Sciences

zabihullahmohaghegh@gmail.com+98 56 3232 3232

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026