Coronavirus infection. Coronavirus infection, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Major Autohemotherapy with common treatments. 100 ml of the patient heparinized blood is mixed with 100 ml of ozone at a concentration of 30micro /mL O2-O3 and inje
Sponsors
Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: Being 20-60 years of age Having a positive reverse-transcriptase polymerase chain reaction test for SARS-CoV-2 Being admitted to the intensive care unit Receiving invasive mechanical ventilation that began a short time before admission or in the intensive care unit
Exclusion criteria
Exclusion criteria: Patients with an anticipated survival length of fewer than 24?hours Patients with a body mass index of 35 kg/m2 and over Patients with a history of blood disorders Patients with a history of renal or liver failure or chronic obstructive pulmonary disease Pregnant or lactating women Patients who were joined in other clinical trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete Blood cell count and diffrential count. Timepoint: Complete Blood cell count and diffrential count at the beginning of the study (before the intervention) and 7, 14 and 21 days after the start of ozone autohemotherapy. Method of measurement: Biochemical analysis.;Liver function tests. Timepoint: Liver function tests at the beginning of the study (before the intervention) and 7, 14 and 21 days after the start of ozone autohemotherapy. Method of measurement: Biochemical analysis.;Renal function tests. Timepoint: Renal function tests at the beginning of the study (before the intervention) and 7, 14 and 21 days after the start of ozone autohemotherapy. Method of measurement: Biochemical analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| Mechanical ventilator weaning time. Timepoint: Mechanical ventilator weaning time during the study after the start of ozone autohemotherapy. Method of measurement: Comment by the treating physician. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDawood Aghamohammadi
Tabriz University of Medical Sciences
Outcome results
None listed