Comparison of the Effectiveness of Vaginal Cream contain extract of Foenicolum vulgar; Salvia officinalis. L; Flaxseed; on Vaginal atrophy in postmenopausal Women

Comparison of the Effectiveness of Vaginal Cream contain extract of Foenicolum vulgar; Salvia officinalis. L; Flaxseed; on Vaginal atrophy in postmenopausal Women referred to selected health care centers undercover of Ahvaz Jundishapour medical university in 1398

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190616043909N1

Enrollment

Registered

2020-04-05

Start date

2019-08-23

Completion date

Unknown

Last updated

2020-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vaginal Atrophy in Postmenopausal Women. Postmenopausal atrophic vaginitis

Interventions

Intervention 1: Intervention group:Foeniculum Vulgare, Salvia Officinalis and Flax Seed extracts vaginal cream, every night, an aplicator for 8 weeks. Intervention 2: Control group: Vaginal gel Placeb

Eligibility

Sex/Gender

Female

Age

45 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 45 to 65; Amenorrhea at less 12 month or have hormone test with FSH level more than 40 unit; Presenting symptom of vaginal atrophy; Have Sexual activity and single partner;

Exclusion criteria

Exclusion criteria: Genital abnormalities; breast diseases with unknown reason; liver cholestatic disorders; renal failure; vaginal infection needing treatment; genital bleeding or spotting with unknown reason; hormone therapy or using sex hormones within the 2 months before the study; using of phytoestrogens such as soy, red clover, fenugreek, and vitex within the last one month; body mass index more than 30 .

Design outcomes

Primary

Measure	Time frame
Symptom of vaginal atrophy. Timepoint: At the beginning of the study, 4 weeks and 8 weeks after intervention. Method of measurement: The most bothersome symptom cheklist.;Clinical signs of vaginal atrophy. Timepoint: At the beginning of the study, 2 weeks, 4 weeks and 8 weeks after intervention. Method of measurement: Check list of clinical signs of vaginal atrophy.;Vaginal maturation index. Timepoint: Before intervention and after intervention. Method of measurement: Vaginal Smear.;Vaginal acidity. Timepoint: Before intervention and after intervention. Method of measurement: PH meter.	—

Measure

Time frame

Symptom of vaginal atrophy. Timepoint: At the beginning of the study, 4 weeks and 8 weeks after intervention. Method of measurement: The most bothersome symptom cheklist.;Clinical signs of vaginal atrophy. Timepoint: At the beginning of the study, 2 weeks, 4 weeks and 8 weeks after intervention. Method of measurement: Check list of clinical signs of vaginal atrophy.;Vaginal maturation index. Timepoint: Before intervention and after intervention. Method of measurement: Vaginal Smear.;Vaginal acidity. Timepoint: Before intervention and after intervention. Method of measurement: PH meter.

—

Secondary

Measure	Time frame
Sexual function. Timepoint: Before and after intervention. Method of measurement: Female Sexual Function Index (FSFI) questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGolshan Tahmasebi

Shahid Beheshti University of Medical Sciences

golshanthm@sbmu.ac.ir+98 61 4362 8502

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026