Skip to content

Effect of Platelet rich Fibrin in gingival thickness

The clinical role of Platelet Rich Fibrin in Increasing the Gingival Thickness and Modifying the Thin Gingival Biotype

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190614043892N1
Enrollment
22
Registered
2019-07-09
Start date
2017-06-05
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

not a disease.

Interventions

Intervention 1: Intervention group: Platelt rich fibrin with tunnel flap. Intervention 2: Control group: Connective tissue graft with tunnel flap.

Sponsors

Damascus University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Patient age range from 18-35 years old with the ability to demonstrate a good oral hygiene Patient were at the first or last stage of orthodontic treatment Subjects should be periodontally and systemically healthy Presence of thin gingival biotype

Exclusion criteria

Exclusion criteria: Patients who were smokers (more than 20 cigarettes a day) patients suffering from systemic diseases or periodontal diseases patients have appliances during orthodontic treatment patients who can’t maintain a good oral hygiene pregnancy or lactating

Design outcomes

Primary

MeasureTime frame
Gingival thickness (GTH). Timepoint: before intervention and 6, 12 months after intervention. Method of measurement: Direct measurement was done with the help of using endodontic file No. (15) with a silicone limiter under local anesthesia. Then the thickness was determined by using electronic digital caliper (High quality LCD Display Electronic Digital Vernier Caliper, china). When the thickness was <1 mm it was categorized as thin biotype and when the thickness was =1 mm it was categorized as thick biotype.

Secondary

MeasureTime frame
Gingival Biotype. Timepoint: 6, 12 months after intervention. Method of measurement: When the thickness was <1 mm it was categorized as thin biotype and when the thickness was =1 mm it was categorized as thick biotype.;Width of keratinized gingiva (WKG). Timepoint: before intervention and 6, 12 months after intervention. Method of measurement: measuring the distance between gingival margin and mucogingival junction.

Countries

Syrian Arab Republic

Contacts

Public ContactMueataz Al-Qershi

Damascus University

mutazalqrashi@yahoo.com+963 11 211 2623

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026