An Investigation of the Interventional Effect of Using Probiotics and Zinc in the Treatment of Admitted Children with Bacterial Pneumonia

An Investigation of the Effect of Using Synbiotic and Zinc in the Treatment of Admitted Children with Bacterial Pneumonia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190611043869N1

Enrollment

135

Registered

2020-05-23

Start date

2019-10-23

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bacterial pneumonia. Bacterial pneumonia, not elsewhere classified

Interventions

Intervention 1: Control group: Antibiotic treatment alone. The type of antibiotic used and the duration of treatment are determined based on the severity of the pneumonia based on the Integrated Manag

Eligibility

Sex/Gender

All

Age

1 Months to 18 Years

Inclusion criteria

Inclusion criteria: Infants and children aged 1 months up to 18 years if diagnosed on medium to very severe bacterial pneumonia Shift left-sided leukocytosis, or Erythrocyte Sedimentation Rate(ESR) and C- Reactive Protein(CRP), or pulmonary involvement in radiography (Basis of clinical, radiographic, and laboratory findings from the Integrated Management of Childhood Illness (IMCI) and Nelson 2016).

Exclusion criteria

Exclusion criteria: Cystic fibrosis, maternal coronary heart disease, immunodeficiency, chronic heart disease, developmental delay, and Failure to Thrive(FTT) (weight for age below the 3rd percentile). Parental dissatisfaction

Design outcomes

Primary

Measure	Time frame
Tachypnea. Timepoint: Daily during hospitalization. Method of measurement: Physical Examination.;Subcostal, Intercostal, Suprasternal Retraction. Timepoint: Daily during Hospitalization. Method of measurement: Physical Examination.;Nasal Flaring. Timepoint: Daily during hospitalization. Method of measurement: Physical Examination.;Temperature. Timepoint: Daily during Hospitalization. Method of measurement: Thermometer.;Respiration Rate. Timepoint: Daily during Hospitalization. Method of measurement: Cornometer.;Cough. Timepoint: Daily during hospitalization. Method of measurement: Physical Examination.;Crackle. Timepoint: Daily during hospitalization. Method of measurement: Physical Examination.;Wheezing. Timepoint: ??Daily during hospitalization. Method of measurement: Physical Examination.	—

Measure

Time frame

Tachypnea. Timepoint: Daily during hospitalization. Method of measurement: Physical Examination.;Subcostal, Intercostal, Suprasternal Retraction. Timepoint: Daily during Hospitalization. Method of measurement: Physical Examination.;Nasal Flaring. Timepoint: Daily during hospitalization. Method of measurement: Physical Examination.;Temperature. Timepoint: Daily during Hospitalization. Method of measurement: Thermometer.;Respiration Rate. Timepoint: Daily during Hospitalization. Method of measurement: Cornometer.;Cough. Timepoint: Daily during hospitalization. Method of measurement: Physical Examination.;Crackle. Timepoint: Daily during hospitalization. Method of measurement: Physical Examination.;Wheezing. Timepoint: ??Daily during hospitalization. Method of measurement: Physical Examination.

—

Secondary

Measure	Time frame
Diarrhea. Timepoint: Daily during hospitalization. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Binesh

Sabzevar University of Medical Sciences

sara76.binesh@gmail.com+98 51 4466 1777

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026