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The effect of Methylprednisolone and Betamethasone on the treatment of lateral epicondylitis

The effect of Methylprednisolone and Betamethasone on the treatment of lateral epicondylitis in patients referred to Shafaihiaian and Rasoul Akram hospitals in Tehran in 2025;A randomized clinical trial study

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190610043858N1
Enrollment
36
Registered
2026-04-20
Start date
2025-07-15
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lateral epicondylitis. Lateral epicondylitis

Interventions

Intervention 1: Intervention group: A- Local injection of Methylprednisolone (40 mg/mL – Iran Hormone Company) administered at the tendinoperiosteal site approximately 2 cm inferior and anterior to th

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with lateral epicondylitis: individuals who, within one to six months prior to entering the study, meet at least two diagnostic criteria in the lateral elbow and forearm region, including tenderness over the lateral epicondyle, positive Cozen’s test: pain occurring in the lateral elbow and forearm during wrist extension against resistance, positive Moudley test: pain occurring in the lateral elbow and forearm during middle finger extension against resistance, positive Chair test: pain occurring in the lateral elbow while lifting a heavy object weighing approximately 3 to 5 kilograms. Age range between 25 and 60 years Pain intensity greater than or equal to 5 based on the Visual Analog Scale (VAS) Obtaining written informed consent No receipt of local interventions such as PRP injections for the treatment of lateral epicondylitis within one to six months prior to study entry No use of NSAIDs, braces, or physiotherapy for the treatment of lateral epicondylitis within two weeks prior to the start of the study

Exclusion criteria

Exclusion criteria: Patients with systemic inflammatory diseases, fibromyalgia syndrome, cervical radiculopathy, or peripheral neuropathy in the upper limb History of allergy to corticosteroids Ipsilateral medial epicondylitis Ipsilateral carpal tunnel syndrome Pregnancy and breastfeeding History of elbow fracture Coagulation disorders or use of anticoagulant medications Patients with psychological disorders Presence of a cardiac pacemaker

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: before and at 2, 6, and 12 weeks after the intervention. Method of measurement: Visual analog scale.

Secondary

MeasureTime frame
Individual's daily function. Timepoint: before and at 2, 6, and 12 weeks after the intervention. Method of measurement: quick DASH , Patient-Rated Tennis Elbow Evaluation (PRTEE).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Saberi

Iran University of Medical Sciences

amirsaberi20@gmail.com+98 21 6435 1000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026