The effect of vitamin D replacement on patients with subclinical hypothyroidism

The effect of Vitamin D Replacement on patients with subclinical hypothyroidism: A randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190610043856N1

Enrollment

Registered

2020-03-17

Start date

2020-01-01

Completion date

Unknown

Last updated

2020-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subclinical Hypothyroidism. Subclinical iodine-deficiency hypothyroidism

Interventions

Intervention 1: Control group:They did not receive vitamin D. Intervention 2: Intervention group: the participants of this group were treated through pearls of vitamin D, produced by Zahravi Pharmacy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subclinical Hypothyroidism Vitamin D Deficiency

Exclusion criteria

Exclusion criteria: Vitamin D replacement therapy in the last 15 months Overt hypothyroidism Those taking medications that affect thyroid function such as steroid and L-thyroxine Patients with symptoms of hypothyroid, Cardiovascular risk factors, Positive TPO antibody Abnormal T4 Pregnant women TSH >10 mIU/l

Design outcomes

Primary

Measure	Time frame
Thyroid stimulating hormone (TSH) between 5 to 10 mU/L. Timepoint: Thyroid-stimulating hormone (TSH) measurement at baseline (before intervention) and 2 months after the intervention. Method of measurement: Enzyme Linked Fluorescence Assay.;Vitamin D deficiency. Timepoint: Vitamin D measurement at baseline (before intervention) and 2 months after the intervention. Method of measurement: Enzyme Linked Flourscience Assay.	—

Measure

Time frame

Thyroid stimulating hormone (TSH) between 5 to 10 mU/L. Timepoint: Thyroid-stimulating hormone (TSH) measurement at baseline (before intervention) and 2 months after the intervention. Method of measurement: Enzyme Linked Fluorescence Assay.;Vitamin D deficiency. Timepoint: Vitamin D measurement at baseline (before intervention) and 2 months after the intervention. Method of measurement: Enzyme Linked Flourscience Assay.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Ahmadi

Fasa University of Medical Sciences

a.ahmadi@fums.ac.ir+98 71 3631 4683

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026