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Prevention of post-cesarean infection

Comparison of cefazolin and cefazolin plus azithromycin regimens in prevention of infection in caesarean section in Shahid Sayyad Shirazi hospital , 2017-2019

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190609043847N1
Enrollment
250
Registered
2019-07-23
Start date
2017-11-21
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Infection caused by cesarean delivery. Condition 2: Infection following a procedure. Infection of obstetric surgical wound Infection following a procedure

Interventions

Intervention 1: The first group received cefazolin 2 g in 30 minutes before cutting. Intervention 2: The second group received 2 grams in 30 minutes of cefazolin before cutting + 500 mg of oral Azithr

Sponsors

Gorgan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Female candidates for non-elective cesarean section, gestational age of 28 weeks and more, no history of infection before surgery, no use of any antibiotic within a week, no use of any antibiotic other than the antibiotics studied, no history Allergy to any medication preterm rupture of membranes less than 24 hours.

Exclusion criteria

Exclusion criteria: Sensitivity to cefazolin or azithromycin Patient unwillingness Get systemic antibiotic in the last 2 weeks Fever prior to cesarean delivery Preterm rupture of membranes more than 24 hours. Get Immunosuppressive Drugs Diseases such as diabetes and immune deficiency Liver disease Kidney and heart failure or pulmonary edema multiple pregnancy pre-eclampsia urinary tract infection or pneumonia Duration of surgery for more than an hour the insertion of subcutaneous ducts during surgery, Abnormal adhesion of placenta

Design outcomes

Primary

MeasureTime frame
The incidence of post-cesarean infection. Timepoint: Infection is recorded two to ten days after admission. Method of measurement: The secretion, erythema, and severe swelling of the site, as well as persistent fever, are checked.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeinab Jalai

Gorgan University of Medical Sciences

dr.jalali.z@goums.ac.ir+98 981732250621

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026