Investigation of the Effect of Local Amitriptyline on the Severity of Gag Reflex

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190608043843N1

Enrollment

Registered

2020-06-18

Start date

2020-06-04

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gag Reflex. Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

Interventions

Intervention 1: Case group: Amitriptyline tablets dissolved in distilled water _ In the amitriptyline group, 75 ml of amitriptyline tablets produced by Pars Daroo Company, which is dissolved in 5 ml o

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: People whose Nausea rate is Higher than 2 using the GTPI Standard Eat Breakfast Two Hours before the Test

Exclusion criteria

Exclusion criteria: Existence of Systemic Diseases Drug Allergy(Amitriptyline or lidocaine) Pregnant and Lactating Women

Design outcomes

Primary

Measure	Time frame
Reduction of Gag reflex. Timepoint: In the amitriptyline group before the intervention and 30 minutes after the intervention in the lidocaine group before the intervention and 5 minutes after the intervention, the nausea reflex is examined. Method of measurement: Gag Trigger Point Index (GTPI).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarnaz Haji Fattahi

Islamic Azad University

dr_h_fattahi@yahoo.com+98 21 2256 4571

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026