Effects of intravenous morphine sulfate and intranasal dexmedetomidine in extremity fractures patients

Comparison of analgesic effects of intravenous morphine sulfate and intranasal dexmedetomidine with alone intravenous morphine sulfate in opoids consumer patients with extremity fractures presented in emergency departments of Shohadaye 7-Tir ?hezrate rasool & firoozgar hospitals

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190608043839N1

Enrollment

Registered

2020-05-26

Start date

2020-06-21

Completion date

Unknown

Last updated

2020-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extremity fractures. Pathological fracture, not elsewhere classified

Interventions

Intervention 1: Intervention group: Patients will receive morphine at a dose of 5 mg plus dexmedetomidine 1.5 mg / kg. Intervention 2: Control group: Patients will receive morphine at a dose of5 mg pl

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Opoids consumer Acute extremity fracture Age Above 18 years old

Exclusion criteria

Exclusion criteria: Low of consciousnesses Chronic renal failure Cirrhosis Pregnancy Alcohol use Heart & vascular disease Psychotropic drugs use

Design outcomes

Primary

Measure	Time frame
Severity of pain after drug administration. Timepoint: After 15, 30, 60 and 120 minutes after drug administration. Method of measurement: Visual Numerical Rating Scale.	—

Secondary

Measure	Time frame
Total dosage of the drug. Timepoint: After the end of treatment. Method of measurement: Based on the information in the patient file.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Amin Zare

Iran University of Medical Sciences

com.yahoo@mazare74+98 21 8670 2503

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026