"Efficacy of Azithromycin versus Erythromycin in premature rupture of membrane"

Efficacy of Azithromycin versus Erythromycin to increase pregnancy length and decrease the neonatal adverse effects in premature rupture of membrane (PROM)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190601043785N1

Enrollment

214

Registered

2019-08-31

Start date

2019-07-01

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premature rupture of membranes. Preterm premature rupture of membranes, unspecified as to length of time between rupture and onset of labor …… unspecified trimester

Interventions

Intervention 1: Intervention group: Azithromycin One gram single dose, PO, produced by Abidi factory, Ampicillin 500 mg intravenous, produced by Abidi factory, every 6 hours for 48 hours, Amoxicillin

Eligibility

Sex/Gender

Female

Age

15 Years to 44 Years

Inclusion criteria

Inclusion criteria: Gestational age between weeks 24 and 32 Have informed consent to enter the study

Exclusion criteria

Exclusion criteria: having hypertension having pre-eclampsia having congenital anomalies

Design outcomes

Primary

Measure	Time frame
Duration of pregnancy. Timepoint: Until delivery. Method of measurement: check list.;Neonatal complications. Timepoint: From birth to discharge. Method of measurement: Baby file.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElham Musavi

Iran University of Medical Sciences

dr1381musavi@gmail.com+98 21 7718 4215

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026