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The effect of Metoclopramide and Ginger capsule in prevention of Laparoscopic Cholecystectomy postoperative vomiting

Comparison of Metoclopramide and Ginger capsule in prevention of Laparoscopic Cholecystectomy postoperative vomiting in Khatam al-Anbiya hospital in Shahroud, Iran in 2019

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190601043782N1
Enrollment
100
Registered
2019-07-16
Start date
2019-07-23
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients underwent laparoscopic cholecystectomy. Disorders of gallbladder, biliary tract and pancreas

Interventions

Intervention 1: Intervention group: 1 g ginger (4 capsules of 250 mg of zintoma from Isfahan Pharmaceutical Company). Intervention 2: Control group: 10 mg oral metoclopramide (4 capsules each containi

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Informed consent to enter the study Indication of laparoscopic cholecystectomy under general anesthesia Ability to swallow capsules

Exclusion criteria

Exclusion criteria: Having any type of cancer Pregnancy Having any disorders with signs of nausea and vomiting like motion sickness ... History of taking anti-nausea and vomiting drugs within three days before surgery History of hypersensitivity to ginger or metoclopramide Bowel obstruction Hepatitis Long-term treatment with corticosteroids Diabetes Obesity (BMI greater than 30) History of digestive problems such as reflux Smoking, alcohol drinking, drug abuse Taking anticoagulants such as aspirin, warfarin, etc. Taking medications that interact with metoclopramide, such as haloperidols, phenothiazines, etc.

Design outcomes

Primary

MeasureTime frame
Nausea. Timepoint: Measure the severity of nausea 30 minutes, 1 hour, 6 hours and 12 hours after surgery. Method of measurement: Visual analogue scale.;Vomiting. Timepoint: Measure the frequency of vomiting 30 minutes, 1 hour, 6 hours and 12 hours after surgery. Method of measurement: According to the patient record.

Secondary

MeasureTime frame
Blood pressure. Timepoint: 30 minutes, 1 hour, 6 hours and 12 hours after surgery. Method of measurement: Mercury pressure gauge.;Pain. Timepoint: 30 minutes, 1 hour, 6 hours and 12 hours after surgery. Method of measurement: Visual analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactYousef kolookhi

Islamic Azad University

dryousefkolookhianestezi@gmail.com+98 23 3239 0360

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026