Effect of Colchicine in patient presenting with non ST-elevation myocardial infarction

Evaluation of the effect of Colchicine therapy in patient presenting with non ST-elevation myocardial infarction

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190601043780N1

Enrollment

140

Registered

2019-08-26

Start date

2019-06-10

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-ST elevation (NSTEMI) myocardial infarction. Non-ST elevation (NSTEMI) myocardial infarction

Interventions

Intervention 1: Intervention group: Patients more than 75 kg of body weight take 1 mg/day colchicine and patients less than 75 Kg of body weight take 0.5 mg/day of colchicine for 4 weeks. Interventio

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient presenting with non ST-elevation myocardial infarction

Exclusion criteria

Exclusion criteria: Patients under hemodialysis GFR 3 times of normal) dyspepsia or chronic diarrhea Under treatment by corticosteroids or immunosuppressive medications Under treatment by verapamil or diltiazem

Design outcomes

Primary

Measure	Time frame
Hs-CRP. Timepoint: At the beginning of the study (before the intervention) and 4 weeks after the start of taking colchicine. Method of measurement: Biochemistry Lab (human hs crp elisa kit).	—

Secondary

Measure	Time frame
Erythrocyte sedimentation rate (ESR). Timepoint: At the beginning of the study (before the intervention) and 4 weeks after the start of taking colchicine. Method of measurement: Biochemistry Lab.;Mean platelet volume. Timepoint: At the beginning of the study (before the intervention) and 4 weeks after the start of taking colchicine. Method of measurement: hematology Lab.;LDL cholesterol. Timepoint: At the beginning of the study (before the intervention) and 4 weeks after the start of taking colchicine. Method of measurement: Biochemistry Lab.	—

Measure

Time frame

Erythrocyte sedimentation rate (ESR). Timepoint: At the beginning of the study (before the intervention) and 4 weeks after the start of taking colchicine. Method of measurement: Biochemistry Lab.;Mean platelet volume. Timepoint: At the beginning of the study (before the intervention) and 4 weeks after the start of taking colchicine. Method of measurement: hematology Lab.;LDL cholesterol. Timepoint: At the beginning of the study (before the intervention) and 4 weeks after the start of taking colchicine. Method of measurement: Biochemistry Lab.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactGholoobi Arash

Mashhad University of Medical Sciences

gholoobia@mums.ac.ir+98 915 514 0084

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026