Comparison of the effect of two methods of brushing with chlorhexidine and Matrica (Chamomile) mouthwash on the incidence of Ventilator-Associated Pneumonia (VAP)

Comparison of the effect of two brushing methods with Chlorhexidine mouthwash and Matricaria (Chamomile) mouthwash on ventilator-induced pneumonia (VAP) in patients admitted to intensive care unit

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190530043773N2

Enrollment

Registered

2020-09-08

Start date

2019-07-23

Completion date

Unknown

Last updated

2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pneumonia. Pneumonia in diseases classified elsewhere

Interventions

Intervention 1: Intervention group (Matricaria chamomilla): Matricaria chamomilla extract at a concentration of 10 percent (made by Adonis Gol Darou Company) administered three times daily with a volu

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patient or guardian consent Severe oral and maxillofacial injury Endotracheal tube Not taking antibiotics before and during hospitalization Lack of immune system disorder Lack of ulcers, infection and oral trauma

Exclusion criteria

Exclusion criteria: Diabetes Immune system disorders Traumatic oral injuries Taking anti-coagulant drugs

Design outcomes

Primary

Measure	Time frame
Ventilator Associated Pneumonia(VAP). Timepoint: Pneumonia on the fifth day after the intervention. Method of measurement: Questionnaire score CPIS(Clinical Pulmonary Infection Score).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRasool Soleimani Moghaddam

Zabol University of Medical Sciences

rasool.solaimani@yahoo.com+98 54 3223 0768

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026