The effect of different levels of positive end-expiratory pressure on hemodynamic parameters in laparoscopic cholecystectomy candidates

Investigating the effect of different levels of positive end-expiratory pressure on hemodynamic parameters in patients candidates for laparoscopic cephalocystectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190528043737N4

Enrollment

Registered

2024-05-21

Start date

2024-05-30

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystectomy. Retained cholelithiasis following cholecystectomy

Interventions

Intervention 1: Intervention group 1: The patient is subjected to mechanical ventilation with specifications TV=6-8cc/kg, RR=12-14 b/m, inspiratory/expiratory ratio=1/2-1/3 and PEEP=0-8cmH2O. Interven

Eligibility

Sex/Gender

All

Age

17 Years to 70 Years

Inclusion criteria

Inclusion criteria: Informed consent Anesthesia class one and two general anesthesia

Exclusion criteria

Exclusion criteria: Severe heart failure Respiratory failure Asthma Chronic obstructive pulmonary disease

Design outcomes

Primary

Measure	Time frame
Hemodynamic symptoms. Timepoint: 30 minutes after intubation, extubation and recovery. Method of measurement: Monitoring.;Capnography. Timepoint: 30 minutes after intubation. Method of measurement: Capnograph.;Heart beat. Timepoint: 30 minutes after intubation, extubation and recovery. Method of measurement: Monitoring.;Arterial blood gases. Timepoint: 30 minutes after intubation, extubation and recovery. Method of measurement: Blood test.	—

Measure

Time frame

Hemodynamic symptoms. Timepoint: 30 minutes after intubation, extubation and recovery. Method of measurement: Monitoring.;Capnography. Timepoint: 30 minutes after intubation. Method of measurement: Capnograph.;Heart beat. Timepoint: 30 minutes after intubation, extubation and recovery. Method of measurement: Monitoring.;Arterial blood gases. Timepoint: 30 minutes after intubation, extubation and recovery. Method of measurement: Blood test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Vatankhah

Bandare-abbas University of Medical Sciences

majid.vatnkhah123@gmail.com+98 76 3333 3280

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026