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Investigating the effect of melatonin and tizanidine on pain and anxiety after cataract surgery

Investigating the effect of melatonin and tizanidine on pain and anxiety after cataract surgery

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190528043737N3
Enrollment
90
Registered
2022-12-06
Start date
2022-12-01
Completion date
Unknown
Last updated
2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract. Infantile and juvenile cataract

Interventions

Intervention 1: The first intervention group: they receive 6 mg of melatonin orally 60 minutes before surgery. Intervention 2: The second intervention group: 4 mg tizanidine orally 60 minutes before s

Sponsors

Bandare-abbas University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with cataract ASA class I or II Consent to participate in the study

Exclusion criteria

Exclusion criteria: History of liver or kidney disease Chronic use of narcotics Prescribing psychotropic drugs Allergy or any contraindication for taking any of the study drugs

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: After the operation in recovery and 24 hours after the operation. Method of measurement: Visual Analogue Scale.;Anxiety. Timepoint: After the operation in recovery and 24 hours after the operation. Method of measurement: Richmond sedation scale.

Secondary

MeasureTime frame
Vital signs. Timepoint: Every five minutes until the end of the operation. Method of measurement: Monitoring.;Nausea and Vomiting. Timepoint: In recovery. Method of measurement: Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrdad Malek Shoar

Bandare-abbas University of Medical Sciences

Mehrdad.malekshoar@hums.ac.i+98 76 3333 3280

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026