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Comparison of the effect of metoclopramide and promethazine in the prevention of postoperative nausea and vomiting

Comparison of the effect of metoclopramide and promethazine in the prevention of nausea and vomiting after laparoscopic cholecystectomy: a double-blind clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190528043737N2
Enrollment
60
Registered
2020-09-17
Start date
2020-03-29
Completion date
Unknown
Last updated
2020-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholecystectomy. Retained cholelithiasis following cholecystectomy

Interventions

Intervention 1: Intervention group1: They receive 10 mg of intravenous metoclopramide. Intervention 2: Intervention group2: They receive 1 mg / kg intravenous promethazine.

Sponsors

Bandare-abbas University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: ASA ???? ?? ? ??

Exclusion criteria

Exclusion criteria: ASA above two Allergy to metoclopramide or promethazine Severe cardiovascular disease Patient with a history of motion sickness History of severe nausea and vomiting after surgery Emergency operation Severe renal and hepatic impairment

Design outcomes

Primary

MeasureTime frame
Nausea-vomiting. Timepoint: Moment of recovery, 30 minutes, first and second hours of recovery. Method of measurement: Vomiting nausea questionnaire.—

Secondary

MeasureTime frame
Blood pressure. Timepoint: Moment of recovery, 30 minutes, first and second hours of recovery. Method of measurement: Monitoring device.;Heart beat. Timepoint: Moment of recovery, 30 minutes, first and second hours of recovery. Method of measurement: Monitoring device.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehrdad Malek Shoar

Bandare-abbas University of Medical Sciences

mdmalekshoar@yahoo.com+98 76 3333 3280

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026