Treatment of depressive symptoms in patients after coronary artery bypass graft surgery

Comparison of bupropion and S citalopram efficacy on depressive symptoms after coronary artery bypass graft surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190525043700N2

Enrollment

100

Registered

2020-07-25

Start date

2020-03-15

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression. Major depressive disorder, single episode, mild

Interventions

Intervention 1: Intervention group1: Treatment with bupropion (Abidi Co) started at 75 mg and gradually increased to 150 mg daily. Intervention 2: Intervention group2: Treatment with S citalopram (Abi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Coronary artery bypass graft surgery Willingness to participate in the study

Exclusion criteria

Exclusion criteria: Patient with cognitive impairment Mental retardation History of substance use Bipolar disorder

Design outcomes

Primary

Measure	Time frame
Patient´s depressive condition. Timepoint: Before intervention (first visit) ,the end of the fourth week (second visit),the end of the eighth week (third visit). Method of measurement: Beck Depression Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRomina Hamzehpour

Babol University of Medical Sciences

r.hamzehpour@mubabol.ac.ir+98 11 3233 8301

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026