Poly-cystic ovary syndrome. Polycystic ovarian syndrome
Conditions
Interventions
Intervention group:oral administration of 40 fecal microbial capsules by each patient in a 3-hour period which is porduce in a laboratory in Bushehr University of Medical Sciences..
Sponsors
Boushehr University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
15 Years to 35 Years
Inclusion criteria
Inclusion criteria: Adult women 15-35 Currently diagnosed PCOS patient without treatment PCOS patient with long time treatment According to Rotterdam criteria patient must have menstural irregularity, hyperandrogenism and PCOS ultrasonography indices and must not have other diseases (at least two criteria) More than 1 month menstural irregularity More than 3 months secondary amenorrhea Hyperandrogenism signs including acnea and hirsutism Hyperandrogenemia (total testosterone of serum >0/5 ng/mL) Non-smoker, without any addiction and non-alcohol consumer patients Obese patient (BMI>20) Abnormal uterine bleeding
Exclusion criteria
Exclusion criteria: Any GI disorders Immuno-compromised patients or usage of immuno-suppressant drugs Improving of PCO symptoms after treatment with drugs Food Allergy Chronic diarrhea Antibiotic intake 3 days before transplantation Any history of cancer Congenital diseases such as adrenal hyperplesia Cushing's disease Acromegaly & Gigantism Type 1& 2 Diabetes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Removal of irregular mensuration. Timepoint: At the beginning of the study (before the intervention) and 7, 28 and 84 days after fecal microbial transplantation. Method of measurement: Questioner.;Removal of ultrasonography PCOS symptoms. Timepoint: At the beginning of the study (before the intervention) and 7, 28 and 84 days after fecal microbial transplantation. Method of measurement: ultrasonography.;Removal of secondary amenorrhea. Timepoint: At the beginning of the study (before the intervention) and 7, 28 and 84 days after fecal microbial transplantation. Method of measurement: Questioner.;Removing hyperandrogenemia. Timepoint: At the beginning of the study (before the intervention) and 7, 28 and 84 days after fecal microbial transplantation. Method of measurement: Questioner and blood sexual hormone concentration.;Decreasing the relative obesity. Timepoint: At the beginning of the study (before the intervention) and 7, 28 and 84 days after fecal microbial transplantation. Method of measurement: Body mass index. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKatayoun Vahdat
Boushehr University of Medical Sciences
Outcome results
None listed