Mild cognitive impairment. Mild cognitive impairment, so stated
Conditions
Interventions
Intervention 1: Active tDCS group
the anodal electrode will be placed on the left dorsolateral prefrontal cortex (DLPFC), which is equivalent to F3 zone according to the standard 10-20 electrode placement system. The cathodal electrod
Both electrodes will be placed as in active group. Current will be applied for 30 seconds (10 seconds ramp-up, 10 seconds 2 mA and 10 seconds ramp-down). The electrodes remain in place for 30 minutes
Sponsors
Guilan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Clinical diagnosis of mild cognitive impairment (MCI) performed by a neurologist based on criteria revised by the National Institute on Aging and Alzheimer's (NIA-AA) in 2012. MMSE score between 19 - 24 age of 50 to 80 years Literacy in Persian Being right-handed
Exclusion criteria
Exclusion criteria: History of dementia or mental retardation Consumption of cognitive enhancers Reversible medical conditions associated with potential cognitive impairment Recent diagnosis of alcoholism or alcohol-based disorders based on the DSM-V Epilepsy Severe clinical conditions include cardiovascular, gastrointestinal, respiratory, endocrine, and CNS diseases History of cerebrovascular surgery Patients who have participated in another clinical study in the last 30 days Contraindications to brain stimulation with tDCS
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Absolute power in different band frequencies in EEG. Timepoint: Before intervention - immediately after intervention - 3 month after intervention. Method of measurement: EEG recording and qEEG analysis with Matlab software. | — |
Primary
| Measure | Time frame |
|---|---|
| Wechsler Memory Scale (WMS). Timepoint: Before intervention - After intervention - 3 month after intervention. Method of measurement: Wechsler Memory Scale (WMS) questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKambiz Rohampour
Guilan University of Medical Sciences
Outcome results
None listed