community acquired sepsis. Other sepsis
Conditions
Interventions
Intervention 1: Intervention group: Patients in this group receive a suspension prepared from a 400 mg pentoxifylline tablet (the tablet is crushed at the time of administration and suspended in water
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Months to 10 Years
Inclusion criteria
Inclusion criteria: A child with sepsis is admitted to the intensive care unit of Akbar Children's Hospital in Mashhad. Meets at least two of the criteria for systemic inflammatory response syndrome Age between 1month and 10 years
Exclusion criteria
Exclusion criteria: children with adrenal insufficiency lack of parental consent for the child s continued participation in the study Those who are known to be intolerant to Methylxanthines and Pentoxifylline
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Heart rate. Timepoint: Daily examinations by an intensive care specialist continue for one week before the intervention begins. Method of measurement: Monitoring Device.;Respiratory rate. Timepoint: Daily examinations by an intensive care specialist continue for one week before the intervention begins. Method of measurement: Monitoring Device.;Blood oxygen saturation. Timepoint: Daily examinations by an intensive care specialist continue for one week before the intervention begins. Method of measurement: Pulse Oximetry.;Blood Pressure. Timepoint: Daily examinations by an intensive care specialist continue for one week before the intervention begins. Method of measurement: Monitoring Device. | — |
Secondary
| Measure | Time frame |
|---|---|
| Length of stay in the intensive care unit. Timepoint: Daily check-ups by the intensive care physician continue for one week before the intervention. Method of measurement: Researcher-made questionnaire.;Need for a ventilator. Timepoint: Daily checks by an intensive care physician continue for one week before the intervention begins. Method of measurement: Temporarily or permanently unable to breathe independently.;Need for a vasopressor. Timepoint: Daily checks by an intensive care physician continue for one week before the intervention begins. Method of measurement: Monitoring device.;Mortality. Timepoint: Daily examinations by an intensive care physician continue for one week from the start of the intervention. Method of measurement: Monitoring device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMajid Sezavar
Mashhad University of Medical Sciences
Outcome results
None listed