The effect of bethanechol and domperidone on oral feeding intolerance

A comparative study of the effect of bethanechol and domperidone on food tolerance in children with food intolerance

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190522043672N5

Enrollment

214

Registered

2023-05-17

Start date

2023-05-22

Completion date

Unknown

Last updated

2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Malabsorption due to intolerance. Malabsorption due to intolerance, not elsewhere classified

Interventions

Intervention 1: Intervention group1: Domperidone in children 0.25 to 0.5 mg/kg, orally 3 or 4 times a day. Intervention 2: Intervention group 2: Children receive bethanechol orally at 0.5 mg/ kg/ da

Eligibility

Sex/Gender

All

Age

1 Months to 18 Years

Inclusion criteria

Inclusion criteria: One month to 18 year children, hospitalized in the pediatric intensive care unit Patients with nutritional intolerance

Exclusion criteria

Exclusion criteria: The cause of intolerance is one of the remediable causes such as electrolyte disorder, constipation or ileus

Design outcomes

Primary

Measure	Time frame
Nutritional tolerance. Timepoint: Daily review from the first day of intervention. Method of measurement: Specialist clinical examinations.	—

Secondary

Measure	Time frame
Possible side effects during hospitalization. Timepoint: Daily examination during hospitalization. Method of measurement: Clinical examination by experts.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Sezavar

Mashhad University of Medical Sciences

sezavardm@mums.ac.ir+98 51 3870 9225

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026