Other side effects of anesthesia and sedation. Other complications of anesthesia
Conditions
Interventions
Intervention 1: Intervention group: Dexmedomidine is injected intravenously. The bolus dose of the drug will be 0.5 micrograms per kilogram and the starting dose of the infusion will be 0.25 microgram
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Months to 18 Years
Inclusion criteria
Inclusion criteria: Suffering from dysfunction of the central nervous system, whether genetic or acquired
Exclusion criteria
Exclusion criteria: Having bradycardia Resistant hypotension during treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of treatment failure and the need for a second sedative drug. Timepoint: The first day, the second day and the third day of the intervention. Method of measurement: Using the Ramsay score table. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of reaching target sedation. Timepoint: The first, second and third day of the intervention. Method of measurement: Measuring time with a timer.;Duration of mechanical ventilation. Timepoint: The day of the patient's discharge. Method of measurement: patient file.;Bradycardia. Timepoint: daily during the intervention period. Method of measurement: Doctor supervision and clinical monitor.;Hypotension. Timepoint: daily during the intervention period. Method of measurement: Mercury sphygmomanometer.;Mortality rate. Timepoint: The last day of hospitalization. Method of measurement: patient file.;Duration of stay in PICU. Timepoint: The day of the patient's discharge. Method of measurement: patient file.;Re-evaluation of Ramsay score in successful patients at 6 hour later in follow-up. Timepoint: in follow-up. Method of measurement: Ramsay sedation scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMajid Sezavar
Mashhad University of Medical Sciences
Outcome results
None listed