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The efficacy of two methods of cryotherapy with intralesional injection of Bloemycin in treatment of anogenital wart

Comparative study on the efficacy of cryotherapy and intralesional injection of Bleomycin in treatment of anogenital wart

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190519043631N1
Enrollment
60
Registered
2019-12-30
Start date
2019-08-23
Completion date
Unknown
Last updated
2020-01-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anogenital wart. Anogenital (venereal) warts

Interventions

Intervention 1: Intervention group 1: Cryotherapy
Liquid nitrogen is applied with a cotton swab on lesions for two Freeze-Taw cycles and then intra-lesional normal saline is injected as a placebo. Intervention 2: Intervention group 2: Intralesional i
The bleomycin vial 15 mg is dissolved in 5 cc normal saline and injected at 2: 1 ratio with lidocaine into the lesions (equivalent to 2 mg /ml).

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with anogenital wart referred to Loghman Hakim and Shohada-e-Tajrish hospitals during the years 2019-2020 Age over 18 years old Having informed consent to participate in the study

Exclusion criteria

Exclusion criteria: Immunodeficiency Drug allergy Other comorbidities such as herpes at the anogenital site Pregnancy and breast feeding Vascular disorders Receiving other treatments in the last 4 weeks (For example Cryotherapy or Imiquimod Ointment) Wart on shaft of penis

Design outcomes

Primary

MeasureTime frame
Treatment of Anogenital wart. Timepoint: At 3-week intervals for 3 times. Method of measurement: Observation by dermatology resident.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNasim Gholizadeh

Shahid Beheshti University of Medical Sciences

nasim.gholizadeh@sbmu.ac.ir+98 21 25719

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 14, 2026