Stress Urinary incontinence. Stress incontinence (female) (male)
Conditions
Interventions
Intervention 1: intervention group: In the stem cell injection group: After obtaining written consent, the mucosal tissue sample is separated from the volunteer patients by the physician and placed in
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Women at least 18 years old history of SUI (Stress Urinary Incontinence) Failure to respond to conservative managements after 3 months Urine leak in the initial examination during coughing or Valsalva maneuver
Exclusion criteria
Exclusion criteria: persistent urinary tract infection (UTI) proved Vesicouretral Reflux (VUR) History of previous Stress urinary incontinence surgery history of neurological diseases such as Cerebro Vascular Accident(CVA) ,muscular dystrophy or Multiple Sclerosis(MS) Obesity (Body Mass Index(BMI)> 40) Localized fibrosis and stiffness at the injection site in the cystoscopy high grade cystocele and rectocele (equal to or more than 3 according to the pelvic organ prolapse quantification system (POP-Q) Overactive bladder symptoms (Uninhibited contractions, low capacity, low compliance in urodynamic study) Medium to severe bladder trabeculation and or open bladder neck in cystourethroscopy Residue of urine > 100cc and or maximum flow rates of lower than 15 ml/s Pregnant or intending future pregnancies coagulation disorders history of Bulking agent injection in urethra
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Examination of stress urinary. Timepoint: 1, 3, 6 and 12 months after the intervention ( surgery or stem cell injection). Method of measurement: International Urinary Incontinence Questionnaire(IIQ score). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahbube Mirzaie
Kerman University of Medical Sciences
Outcome results
None listed