Keratoconus. Keratoconus
Conditions
Interventions
Intervention 1: Intervention group 1: (continuous-light accelerated CXL group)
Accelerated CXL with continuous-light using 9 mW/cm2 for 10 minutes . Intervention 2: Intervention group 2: (pulsed-light accelerated CXL group)
Accelerated CXL with pulsed on/off light using 9 mW/cm2 for 10 minutes.
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
6 Years to 30 Years
Inclusion criteria
Inclusion criteria: Progressive keratoconus (Progression of the disease was considered as confirmed if the loss of corrected distance visual acuity (CDVA) was more than one line in 1 year, or when the topographic keratometry increased by >1.0 D in 6 months or >2.0 D in 12 months) The thinnest central corneal thickness (CCT) >400 µm
Exclusion criteria
Exclusion criteria: Patients who wear contact lenses for one month prior to the initial evaluation and treatment Patients with immune system disorders Patients with corneal scar Patients with history of herpes simplex keratitis Patients who were pregnant or breastfeeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Best corrected spectacle visual acuity (BSCVA). Timepoint: 6 months after intervention. Method of measurement: E-chart. | — |
Secondary
| Measure | Time frame |
|---|---|
| Keratometric indices. Timepoint: 6 months after intervention. Method of measurement: Pentacam.;Biomechanical parameters. Timepoint: 6 months after intervention. Method of measurement: Corvis. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNasrin Masihpour
Shiraz University of Medical Sciences
Outcome results
None listed