Meibomian gland dysfunction. Evaporative dry eye- dry eye syndrome
Conditions
Interventions
Intervention 1: Intervention group: 50 patients with meibomian gland dysfunction will undergo 3 sessions of intense pulse light therapy. Meanwhile routine dry eye therapy consisting using artificial t
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with a diagnosis of meibomian gland dysfunction according to international diagnostic criteria Patients who have ethical consent for participating in the study Patients who have the history of at least 2 months taking current medications for meibomian gland dysfunction.
Exclusion criteria
Exclusion criteria: Having any ocular or systemic disease Having any history of ophthalmic surgeries Taking medications with photo sensitivity side effects Contact lens wearers Having nevus or tattoos in palpebral and peri orbital region
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OSDI score: this ocular surface index questionnaire consists of 12 question and assesses the severity of dry eye. Timepoint: Baseline, day 14, day 45, day 75. Method of measurement: sum of score of questionnaire which has been filled by the patients.;TBUT : tear break up time. Timepoint: Baseline, day 14, day 45, day 75. Method of measurement: keratograph, slit lamp.;Osmolarity: tear film density. Timepoint: baseline, day 75. Method of measurement: tear lab device. | — |
Secondary
| Measure | Time frame |
|---|---|
| Meibomian gland drop out which is graded from 0 to 3. Timepoint: baseline, day 14, day 45, day 75. Method of measurement: keratograph device.;PSQI: Pittsburgh sleep quality index. Timepoint: BASELINE, DAY 75. Method of measurement: Sum of score of questionnaire which has been filed by the patients. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSamira Hassanzadeh
Mashhad University of Medical Sciences
Outcome results
None listed