Condition 1: Diabetes. Condition 2: Vitamin D deficiency. Type 2 diabetes mellitus Vitamin D deficiency
Conditions
Interventions
Intervention 1: Intervention group: In this group patients will be treated by oral 50000 IU vitamin D3 capsule(cholecalciferil), once every week for 12 weeks. The capsule manufacture in Zahravi pharma
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 85 Years
Inclusion criteria
Inclusion criteria: It's been over 2 years since the diagnosis of type 2 diabetes Detection of Type 2 diabetes according to standard criteria HbA1C criteria range from 8-7 Fasting Blood glucose under 200 Using of oral Glucose-lowering Agents Not taking vitamin D and calcium supplements at least 3 months ago, not taking medications that affect vitamin D metabolism (corticosteroids, calcitonin, cytotoxic drugs and immunosuppressive drugs, anticonvulsants) at least 3 months ago, lack of diseases that affect the metabolism of vitamins D effects (such as liver, endocrine, and cancer) Desire to cooperate in designing and completing a written questionnaire he level of vitamin D is between 10 and 19.9 Age between 30-85
Exclusion criteria
Exclusion criteria: Malnutrition, Infertility, Oligomenorrhea, Pregnancy, Breastfeeding, Malignancy Smoking, alcohol consumption Immobilization for more than a week Acute and chronic active infections, acute and chronic inflammatory diseases, cardiovascular, liver, kidney, thyroid and parathyroid disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glycosylated hemoglobin(HbA1c). Timepoint: Before starting the study and 12 weeks after starting vitamin D. Method of measurement: Laboratory.;Vitamin D levels. Timepoint: Before starting the study and 12 weeks after starting vitamin D. Method of measurement: Laboratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in level of liver enzymes(AST-ALT-ALK). Timepoint: Before the study began and 12 weeks later. Method of measurement: laboratory.;Changes in lipid profiles (LDL-HDL-TG). Timepoint: Before the study began and 12 weeks later. Method of measurement: laboratory.;Renal Profile Changes (BUN-Creatinine). Timepoint: Before the study began and 12 weeks later. Method of measurement: laboratory. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHajmoradi Hamed
Kashan University of Medical Sciences
Outcome results
None listed