Effects of low-intensity training on patients with Alzheimer's disease

The effect of twelve weeks of low intensity combined exercise with visual stimulation on cognitive and physical performance and brain wave changes of Alzheimer's patients

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190504043468N1

Enrollment

Registered

2020-08-05

Start date

2019-12-21

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's disease. Alzheimer disease with early onset

Interventions

Intervention 1: Intervention group: Low-intensity compound exercises. The participants in the intervention group will perform 24 workouts twice a week for 12 weeks. Each session lasts about 40-60 minu

the distance between the obstacles is variable. In the third part, the participants cross over a safe balance beam board (2 m) with eyes closed (two repetitions in the first three sessions, gradually

Eligibility

Sex/Gender

All

Age

50 Years to 75 Years

Inclusion criteria

Inclusion criteria: age range (50 -70 yr) ability to do exercise stage 1 and 2 Alzheimer's disease

Exclusion criteria

Exclusion criteria: Patients who are unable to walk or stand Patients suffering from Alzheimer's disease due to severe depression Alzheimer's patients who have this disease because of a heart attack Alzheimer's patients who develop Alzheimer's due to obstruction of the cerebrovascular system Patients with cardiovascular problems who are not allowed to exercise by their doctor

Design outcomes

Primary

Measure	Time frame
Cognitive changes. Timepoint: Once before practicing and once again at the end of twelve weeks of practice. Method of measurement: The questionnaire was based on the diagnosis of a physician and SPMSQ, cognitive status questionnaire MMSE; mental status brief examination ; Knowledgeable cognitive decline questionnaire on IQCDE ; The European dimension of the five dimensional quality of life D-EuroQol; Depression Scale of the Elderly GDS;.;Physical performance. Timepoint: Once before practicing and once again at the end of twelve weeks of practice. Method of measurement: The chair sit and reach test; Maximal isometric handgrip strength test; The timed up and go; The six minute walk test;.;Memory. Timepoint: Once before practicing and once again at the end of twelve weeks of practice. Method of measurement: ROLAND RUDAS global demographics scale.	—

Measure

Time frame

Cognitive changes. Timepoint: Once before practicing and once again at the end of twelve weeks of practice. Method of measurement: The questionnaire was based on the diagnosis of a physician and SPMSQ, cognitive status questionnaire MMSE; mental status brief examination ; Knowledgeable cognitive decline questionnaire on IQCDE ; The European dimension of the five dimensional quality of life D-EuroQol; Depression Scale of the Elderly GDS;.;Physical performance. Timepoint: Once before practicing and once again at the end of twelve weeks of practice. Method of measurement: The chair sit and reach test; Maximal isometric handgrip strength test; The timed up and go; The six minute walk test;.;Memory. Timepoint: Once before practicing and once again at the end of twelve weeks of practice. Method of measurement: ROLAND RUDAS global demographics scale.

—

Secondary

Measure	Time frame
Brain waves changes. Timepoint: Once before practicing and once again at the end of twelve weeks. Method of measurement: electroencephalogram.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSadegh Amani-Shalamzari

Kharazmi University

amani_sadegh@yahoo.com+98 26145796000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 16, 2026