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Effect of general anesthesia on cognitive function

Effect of general anesthesia on postoperative cognitive function: A clinical trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190429043414N2
Enrollment
100
Registered
2019-07-12
Start date
2019-07-23
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive dysfunction. Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances

Interventions

Intervention group: The intervention group will receive general anesthesia according to standard methods. The type of medications may not be the same in all cases, but they will be administered based

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 60 years of age or higher ASA I or II candidates for surgery under general anesthesia

Exclusion criteria

Exclusion criteria: History of alcohol consumption History of drug abuse consumption History of sedative drug consumption History of anticonvulsant drug consumption General anesthesia contraindications Cardiac failure Acute renal failure Acute liver failure Respiratory failure Bleeding disorders Myocardial infarction within the previous 6 weeks Stroke within the previous 6 months Progressive neurological disorders

Design outcomes

Primary

MeasureTime frame
The amount and severity of postoperative cognitive dysfunction. Timepoint: Before, immediately after, and 10 months after spinal anesthesia. Method of measurement: Wechsler Memory Scale-III (WMS-III) and the Mini Mental State Examination (MMSE).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Kimiaei Assadi

Hamedan University of Medical Sciences

hkimiaeimd@yahoo.com+98 81 3525 0182

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026