Postoperative cognitive dysfunction. Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 60 years of age or higher ASA I or II candidates for surgery under general anesthesia
Exclusion criteria
Exclusion criteria: History of alcohol consumption History of drug abuse consumption History of sedative drug consumption History of anticonvulsant drug consumption General anesthesia contraindications Cardiac failure Acute renal failure Acute liver failure Respiratory failure Bleeding disorders Myocardial infarction within the previous 6 weeks Stroke within the previous 6 months Progressive neurological disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amount and severity of postoperative cognitive dysfunction. Timepoint: Before, immediately after, and 10 months after spinal anesthesia. Method of measurement: Wechsler Memory Scale-III (WMS-III) and the Mini Mental State Examination (MMSE). | — |
Countries
Iran (Islamic Republic of)
Contacts
Hamedan University of Medical Sciences