Effect of spinal anesthesia on postoperative cognitive dysfunction

Effect of spinal anesthesia on the amount of postoperative cognitive dysfunction: A clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190429043414N1

Enrollment

100

Registered

2019-05-25

Start date

2019-05-22

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive dysfunction. Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances

Interventions

Intervention group: The intervention group will receive 10-12 mg of bupivacaine 0.5% with 50 µg fentanyl for spinal anesthesia..

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: 60 years of age or higher ASA I candidates for surgery under spinal anesthesia ASA II candidates for surgery under spinal anesthesia

Exclusion criteria

Exclusion criteria: History of alcohol and sedative as well as anticonvulsant drug consumption, and drug abuse Spinal anesthesia contraindications (local infection on the spinal needle region, sepsis, bleeding disorders, low platelet count, utilization of anticoagulants, brain lesions, anatomical disorders on spinal cord, and loss of blood volume)

Design outcomes

Primary

Measure	Time frame
The amount and severity of postoperative cognitive dysfunction. Timepoint: Before, immediately after, and 10 months after spinal anesthesia. Method of measurement: Wechsler Memory Scale-III (WMS-III) and the Mini Mental State Examination (MMSE).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Kimiaei Assadi

Hamedan University of Medical Sciences

hkimiaeimd@yahoo.com+98 81 3525 0182

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026