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platelet rich fibrin in orthognathic surgery

Evaluation of using platelet rich fibrin in increase of lefort I osteotomy stability in orthognathic surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190429043413N1
Enrollment
40
Registered
2019-05-25
Start date
2017-04-20
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

skeletal class III deformity. Other congenital deformities of skull, face and jaw

Interventions

Intervention 1: Intervention group: patients who undergo lefort I osteotomy for maxillary advancement. in this group, after osteotomy, maxilla was fixated in appreciate position by 4 plates. 10cc bloo
but not received platelet rich fibrin on osteotomy line.

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: patients with skeletal class III deformity candidate for maxillary advancement

Exclusion criteria

Exclusion criteria: patients who need maxillary setback patients with previous cleft lip or palate who need orthognatic surgery patients with history of radiation on head and neck or bisphosphonate therapy or any systemic diseases that affected on bone healing

Design outcomes

Primary

MeasureTime frame
Amount of skeletal relapse at vertical dimension. Timepoint: immediately after surgery, 6 to 12 months after surgery. Method of measurement: measurement of point A to sella-nasion (SN) line change.;Amount of skeletal relapse at horizontal dimension. Timepoint: immediately after surgery, 6 to 12 months after surgery. Method of measurement: measurement of point A to sella-nasion (SN) perpendicular line change.

Secondary

MeasureTime frame
Amount of maxillary movement after surgery at horizontal dimension. Timepoint: before surgery, immediately after surgery. Method of measurement: measurement of point A to sella-nasion (SN) perpendicular line change.;Amount of maxillary movement after surgery at vertical dimension. Timepoint: before surgery, immediately after surgery. Method of measurement: measurement of point A to sella-nasion (SN) line change.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPedram Bakhshaei

Shahid Beheshti University of Medical Sciences

bakhshaei.pedram@gmail.com+98 21 2243 2560

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026