Patients undergoing rhinoplasty with lateral osteotomy. Encounter for cosmetic surgery
Conditions
Interventions
Intervention 1: Intervention group: The side of the nose that is randomly selected and receives a 1cc injection of local PRF solution is considered the intervention group. For this purpose, at the end
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Written informed consent Ability to follow protocol and attend follow-up visits Patients who are scheduled for a lateral osteotomy (as part of a rhinoplasty or specific procedure) and have been approved by their physician Physical condition suitable for surgery Women of childbearing age must either use an effective method of contraception or have a negative pregnancy test within 72 hours prior to surgery. Blood pressure within normal range
Exclusion criteria
Exclusion criteria: Known coagulation disorders or history of pathological bleeding (hemophilia, severe thrombocytopenia, etc.) Continuous use of anticoagulant or antiplatelet drugs (such as warfarin, new anticoagulant drugs, clopidogrel, aspirin at therapeutic doses) that cannot be discontinued according to the doctor's advice Active acute or inflammatory infection in the nasopharynx/facial area or active systemic infection History of severe systemic disease (e.g., heart failure class III–IV, end-stage renal disease, significant hepatic impairment, or ASA more than or equal to III) Uncontrolled diabetes or other metabolic disorders that increase the risk of repair Use of immunosuppressive drugs (eg, cyclophosphamide, high doses of systemic corticosteroids within the last 4 weeks, biologics) that can affect healing or the risk of infection. Recent intravenous use or infusion of a blood or plasma product that would interfere with PRF preparation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: One week and one month after the intervention was completed. Method of measurement: A visual analog scale (VAS) questionnaire will be used to measure pain.;Ecchymosis. Timepoint: One week and one month after the intervention was completed. Method of measurement: Clinical examination.;Swelling. Timepoint: One week and one month after the intervention was completed. Method of measurement: Clinical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNasim Raad
Shahid Beheshti University of Medical Sciences
Outcome results
None listed