patient with major burn 25-50 percent.
Conditions
Interventions
Intervention 1: Intervention group: one synbiotic capsule one hour after breakfast until 15 days. Intervention 2: Control group: one capsule (placebo, exactly as like as synbiotic capsule) one hour af
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Burn percent 25-50 No use of any prebiotic, probiotic or synbiotic in last 2 months before the study starts Patients with stable condition
Exclusion criteria
Exclusion criteria: Use of dopamine and epinephrine Pregnancy and breast feeding Allergy to melatonin Bowel obstruction - ileus - gastroparesy or any condition that affect enteral absorption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Positive sputum culture. Timepoint: After 15 days of synbiotic or placebo prescription. Method of measurement: Sputum culture.;Positive blood culture. Timepoint: After 15 days of synbiotic or placebo prescription. Method of measurement: Blood culture.;Positive urinary culture. Timepoint: After 15 days of synbiotic or placebo prescription. Method of measurement: Urinary culture.;Positive catheter infection. Timepoint: After 15 days of synbiotic or placebo prescription. Method of measurement: Clinician examination - catheter culture. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactA?li Ahmad Abadi
Mashhad University of Medical Sciences
Outcome results
None listed