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" Effect of Glycyrrhiza glabra extract on salivary volume"

Evaluation of the effect of Glycyrrhiza glabra extract in the form of D-Reglis herbal pills on amount of human Saliva: A Crossover randomized clinical trial study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190422043344N1
Enrollment
20
Registered
2019-06-17
Start date
2019-03-05
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention 1: Intervention group: A single dose of 380 milligrams of licorice extract produced by Iran Daruk Co., with 200 cc was prescribed.To prevent the bias between the drug and the placebo, the

Sponsors

Bojnourd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers who have no history of dry mouth aged 18-35 years Signature of informed consent form

Exclusion criteria

Exclusion criteria: 1- Pregnancy 2. Those who suffer from dry mouth and take medication 3. Sensitivity to licorice 4- Use of cigarettes 5- Drug use in the previous month before the study

Design outcomes

Primary

MeasureTime frame
The weight of saliva secreted from all salivary glands in the mouth. Timepoint: Measurement of saliva volume at the beginning of the study and at 20, 40, 60, 90, 120, and 180 minutes after the administration of the D-REGLIS tablet and placebo. Method of measurement: digital Balance.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehdi Mohammad Sadeghian

Bojnourd University of Medical Sciences

dr.mm.sadeghian@gmail.com+98 58 3226 1272

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026