the effect of hemorrhage preventing medication

Evaluating the effect of Tranexamic acid on brain contusion and intracerebral hemorrhage in patients with traumatic brain injury (TBI)

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190422043339N1

Enrollment

Registered

2021-12-03

Start date

2018-09-23

Completion date

Unknown

Last updated

2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intracranial hematoma and contusion. Focal traumatic brain injury

Interventions

Intervention 1: Intervention group: Tranexamic acid made in Iran and Iran Daru Pharmaceutical Company is infused with an initial dose of 1 g per 100 ml of serum within 10 minutes and then infused with

Eligibility

Sex/Gender

All

Age

13 Years to No maximum

Inclusion criteria

Inclusion criteria: All patients over 13 years of age with blunt traumatic brain injury were referred to the emergency department less than 3 hours after the accident. Patients on CT scan have cerebral intraparenchymal hemorrhage upon arrival.

Exclusion criteria

Exclusion criteria: Major damage to organs requiring surgical intervention within the first 3 hours Get any medication that disrupts homeostasis

Design outcomes

Primary

Measure	Time frame
Brain contusion. Timepoint: At baseline, 24 and 48 hours after injection. Method of measurement: Brain CT scanning.;Intracerebral hemorrhage. Timepoint: At baseline, 24 and 48 hours after injection. Method of measurement: Brain CT scanning.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEsmaeel Fakharian

Kashan University of Medical Sciences

efakharian@gmail.com+98 31 5554 0026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026