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The effect of nicotine on cognitive function

The Effect of Nicotine on Cognitive functions and Positive Affection in individual with Mild Cognitive Impairment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20190418043313N1
Enrollment
30
Registered
2022-01-13
Start date
2019-05-02
Completion date
Unknown
Last updated
2022-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment. Mild cognitive impairment, so stated

Interventions

Intervention 1: Intervention group: Each member of the intervention group was given a chewing gum made by Nikolife Company containing 2 mg of nicotine at a time and the participants chewed it for 2 ho

Sponsors

Islamic Azad University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Male patients Age between 20 and 60 years Have a definitive diagnosis of mild cognitive impairment No risk of heart and brain disease No use of psychiatric drugs No risk of hypertension Not being a smoker

Exclusion criteria

Exclusion criteria: Having severe cognitive impairment Inability to communicate with researcher and answer the questionnaire

Design outcomes

Primary

MeasureTime frame
Working memory score in Wechsler Memory Scale. Timepoint: Before and after 2 hours of intervention. Method of measurement: Wechsler Memory Scale.;Positive affect score in PANAS questionnaire. Timepoint: Before and after 2 hours of intervention. Method of measurement: Positive and Negative Affect Schedule (PANAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEsmail Khodadadi

Islamic Azad University

esmailkhodadadi11@gmail.com+98 41 3331 8681

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026