Craniotomy. Traumatic amputation of other parts of head
Conditions
Interventions
Intervention 1: Intervention group: Intervention group 1:We inject 1 micro gram in kilogram Dexmedetomidine in loading dose ? and 0.5 micro gram in kilogram Dexmedetomidine in hours in Infusion. Inter
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients with head trauma Patients with ASA class I and II Patients that the informed written consent form has been fillede out by their legal gurdian in order to participate in the study Candidates of craniotomy due to severe head trauma Patients with severe head trauma candidates of craniotomy with a maximum operation duration of 150 min Patients with severe head trauma candidates of craniotomy that are operated by a neurosurgeon Patients with severe head trauma candidates of craniotomy aged between 15-75 years
Exclusion criteria
Exclusion criteria: Patients with severe head trauma candidates of craniotomy which have hypersensitivy to dexmedetomidine and metoprolol Patients with severe head trauma candidates of craniotomy that their legal gurdian refuse the informed written consent for participation in the study. Patients with a past medical history of cardio-vascvular diseases, uncontrolled diabetes, seizure and epilepsy, renal failure, liver failure, coagulation disorders, previous cerebrovascular accident or recent myocardial infarction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding. Timepoint: Every 15 minutes to end of surgery. Method of measurement: Observation.;Mortality. Timepoint: After surgery. Method of measurement: observation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Alireza Kamali
Arak University of Medical Sciences
Outcome results
None listed