Comparison sedative effect of Dexmedetomidin & midazolam

Comparison of sedative effect of dexmedetomidine and midazolam in patients undergoing EUS procedure outside the operating room

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190417043295N1

Enrollment

126

Registered

2020-02-21

Start date

2019-04-21

Completion date

Unknown

Last updated

2020-02-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: patients undergoing gastrointestinal Endosonography outside the operating room. Condition 2: . Functional dyspepsia

Interventions

Intervention 1: Intervention group: Dexmedetomidine 1 ug/kg inf. for 10 min, propofol 0.5 mg/kg and fentanyl bolous. Intervention 2: Control group: Midazolam inf. for 10 min, propofol 0.5 mg/kg and fe

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Candidates for gastrointestinal endosonography Declaration of consent for entry into the study and signature of the consent form Anesthesia ASA class I and II Age range 18 to 65 years

Exclusion criteria

Exclusion criteria: Renal Failure Liver Failure Sensitivity to the drugs studied Drug addiction Chronic pain syndromes Cardiovascular disease Respiratory disease

Design outcomes

Primary

Measure	Time frame
Rate of Sedation (RAMSAY index). Timepoint: during endo-sonography procedure. Method of measurement: Ramsay Sedation Scale.;Pain. Timepoint: Before, during and 1 hour after procedure. Method of measurement: Ambesh Pain score.;Nausea and vomiting. Timepoint: Before, during and 1 hour after procedure. Method of measurement: (VAS) Visual analogue scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Baghbanian

Ahvaz University of Medical Sciences

baghbanian.r@ajums.ac.ir+98 61 3292 3985

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026