Assessment of the effect of Portulaca oleracea on hyperthyroidism

Assessment of the effect of hydroalcoholic extract of Portulaca oleracea on thyroid hormones in hyperthyroidism

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190415043279N5

Enrollment

Registered

2020-07-11

Start date

2020-07-22

Completion date

Unknown

Last updated

2020-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hyperthyroidism. Thyrotoxicosis, unspecified

Interventions

Intervention 1: Intervention group: Capsule containing hydroalcoholic extract of Portulaca oleracea plant at dose of 400 mg three times a day for two consecutive months. These oral capsules of hydroal

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Recently diagnosed hyperthyroid patients

Exclusion criteria

Exclusion criteria: Pregnancy Children Cardiovascular disease Ophthalmopathy Thyroiditis

Design outcomes

Primary

Measure	Time frame
Serum TSH levels. Timepoint: Measurement of TSH levels before the intervention and two months later. Method of measurement: ELISA.;Serum T4 levels. Timepoint: Measurement of T4 levels before the intervention and two months later. Method of measurement: ELISA.;Serum T3 levels. Timepoint: Measurement of T3 levels before the intervention and two months later. Method of measurement: ELISA.;Body Mass Index. Timepoint: Measurement of BMI before the intervention and two months later. Method of measurement: According to the BMI formula (BMI = (weight in kilograms) divided by (Height in meters squared)).	—

Measure

Time frame

Serum TSH levels. Timepoint: Measurement of TSH levels before the intervention and two months later. Method of measurement: ELISA.;Serum T4 levels. Timepoint: Measurement of T4 levels before the intervention and two months later. Method of measurement: ELISA.;Serum T3 levels. Timepoint: Measurement of T3 levels before the intervention and two months later. Method of measurement: ELISA.;Body Mass Index. Timepoint: Measurement of BMI before the intervention and two months later. Method of measurement: According to the BMI formula (BMI = (weight in kilograms) divided by (Height in meters squared)).

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShahnaz Ghafouri

Sanandaj University of Medical Sciences

drghafoorish76@gmail.com+98 87 3366 4645

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026