Evaluation of the effect of probiotic supplementation on the proteinuria

Evaluation of the effect of probiotic supplementation on the improvement of proteinuria in patients with immunoglobulin A nephropathy

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190415043279N11

Enrollment

120

Registered

2022-03-07

Start date

2022-04-04

Completion date

Unknown

Last updated

2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

IgA nephropathy. Diabetes mellitus due to underlying condition with diabetic nephropathy

Interventions

Intervention 1: Intervention group: Omega 3 capsules 1000 mg and Valsartan in addition to probiotic capsules of Milad Pouya Company Probiotic Capsules, approved by the US Food and Drug Administration

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age over 18 years Early IgA nephropathy diagnosed by biopsy Albuminuria more than 0.75 grams per day Serum creatinine less than 200 micromoles per liter Creatinine clearance greater than 30 ml per minute

Exclusion criteria

Exclusion criteria: Inflammatory diseases Diabetes Celiac Cancer AIDS Autoimmune diseases Pregnancy Breastfeeding Secondary IgA nephropathy Allergy to probiotics

Design outcomes

Primary

Measure	Time frame
Body Mass Index (BMI). Timepoint: At the beginning of the study (before the intervention) and after the intervention. Method of measurement: by measuring height and weight using a scale and height meter.;24-hour urinary protein level. Timepoint: At the beginning of the study (before the intervention) and after the intervention. Method of measurement: laboratory kit.;Duration of illness. Timepoint: Examination by a nephrologist once every two months until the end of the 6-month period (three times). Method of measurement: Patient file.;Side effects. Timepoint: Periodically every month until the end of 6 months. Method of measurement: Telephone contact with patients.	—

Measure

Time frame

Body Mass Index (BMI). Timepoint: At the beginning of the study (before the intervention) and after the intervention. Method of measurement: by measuring height and weight using a scale and height meter.;24-hour urinary protein level. Timepoint: At the beginning of the study (before the intervention) and after the intervention. Method of measurement: laboratory kit.;Duration of illness. Timepoint: Examination by a nephrologist once every two months until the end of the 6-month period (three times). Method of measurement: Patient file.;Side effects. Timepoint: Periodically every month until the end of 6 months. Method of measurement: Telephone contact with patients.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohammad saad Forghani

Sanandaj University of Medical Sciences

drforghani@yahoo.com+98 87 3366 4645

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026