Effect of Trachyspermum ammi in the reduction of bleeding in patients with IBD

Effect of Ethanolic extract of Trachyspermum ammi as adjuvant in the reduction of bleeding in patients with IBD

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190415043279N10

Enrollment

Registered

2021-03-05

Start date

2021-02-19

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative colitis. Ulcerative colitis

Interventions

Intervention 1: Intervention group: Capsule containing Ethanolic extract of Trachyspermum ammi at two dose of 250 mg per day for three consecutive months. These oral capsules of Ethanolic extract of T

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Age 18 to 75 years Patients diagnosed with Ulcerative colitis by a gastroenterologist

Exclusion criteria

Exclusion criteria: Crohn's disease Pregnancy Breastfeeding History of allergy to herbal medicines

Design outcomes

Primary

Measure	Time frame
Number of daily bowel movements. Timepoint: Beginning and end of the intervention. Method of measurement: Disease Activity Questionnaire.;Daily rectal bleeding. Timepoint: Beginning and end of the intervention. Method of measurement: Disease Activity Questionnaire.;Classification of bleeding according to symptoms and tests by a physician. Timepoint: Beginning and end of the intervention. Method of measurement: Disease Activity Questionnaire.;Fecal occult blood. Timepoint: Beginning and end of the intervention. Method of measurement: Stool test.;Blood Hemoglobin. Timepoint: Beginning and end of the intervention. Method of measurement: CBC test.;C-Reactive Protein. Timepoint: Beginning and end of the intervention. Method of measurement: Agglutination method.;Erythrocyte sedimentation rate (ESR). Timepoint: Beginning and end of the intervention. Method of measurement: ESR device.	—

Measure

Time frame

Number of daily bowel movements. Timepoint: Beginning and end of the intervention. Method of measurement: Disease Activity Questionnaire.;Daily rectal bleeding. Timepoint: Beginning and end of the intervention. Method of measurement: Disease Activity Questionnaire.;Classification of bleeding according to symptoms and tests by a physician. Timepoint: Beginning and end of the intervention. Method of measurement: Disease Activity Questionnaire.;Fecal occult blood. Timepoint: Beginning and end of the intervention. Method of measurement: Stool test.;Blood Hemoglobin. Timepoint: Beginning and end of the intervention. Method of measurement: CBC test.;C-Reactive Protein. Timepoint: Beginning and end of the intervention. Method of measurement: Agglutination method.;Erythrocyte sedimentation rate (ESR). Timepoint: Beginning and end of the intervention. Method of measurement: ESR device.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Farshad Sheikhesmaeili

Sanandaj University of Medical Sciences

dr_s_smaili@yahoo.com+98 87 3366 4645

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026