Comparison Of The Effect Of Misoprostol On Induction Of Labour In Term Pregnancy: Double Blind Randomized Clinical Trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20190415043278N1

Enrollment

300

Registered

2019-05-27

Start date

2019-05-22

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Reduce The Duration Of Induction To Delivery In Pregnant Mothers.

Interventions

Intervention 1: Intervention group: vaginal misoprostol. Intervention 2: Intervention group: sub lingual misoprostol. Intervention 3: Intervention group: cervical misoprostol. Intervention 4: Control

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Single Viable Term Fetus, Gestational Age>=39 Week, Fetal Weight 5, Nst Active ,No Pelvic Stricture, Bishop Score <5 ,IUGR Grade 1, Mild Diabetic, Pre eclampsia, Chronic Hypertension ,PPROM, Post Date Pregnancy

Exclusion criteria

Exclusion criteria: IUGR Grade >1,Fetus Malformation , Previous Uterine Scar , Multi Parity >2 , OT>38 ,Chorioamnionitis , Olygo & Poly Hydramniotic ,Macrosomia , Nst Non Reactive ,History of a Mothers Seizure , Hypotension-Renal & Heart Diese, Gestational Age < 36 Week.

Design outcomes

Primary

Measure	Time frame
Comparison Of The InitiationI Induction Interval And The Time Of Onset Of Pain In The Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) In Qazvin. Timepoint: Admision in Labure. Method of measurement: Time.;Comparison Of The Duration Of Induction To Delivery In Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) In Qazvin. Timepoint: Admision in Labure. Method of measurement: Time.;3) Comparison Of Delivery Type In Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) In Qazvin. Timepoint: Admision in Labure. Method of measurement: NVD , C/S.;Comparison Of The Complications Of Clinical And Uterine Medication In Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) In Qazvin. Timepoint: Admision in Labure. Method of measurement: Tachycardia (presence Of 5 Or More Uterine Contractions In 10 minutes), Excessive Uterine Stimulation (Any Condition That Causes Abnormal Fetal Heart Rate), Uterine Hypertonia (Any Uterine Contraction Lasting More Than Two Minutes), Start Time Suitable Contractions Of Uterus, Interval Between Initiation Of Induction And Delivery, Type Of Delivery, Meconium Excretion, Fetal Death, Apgar Score In the First And Fifth Minutes, And The Need For NICU Neonates Due To Low Apgar Score And Side Effects Of The Drug. Digestive Complications Include Nausea, Vomiting, Diarrhea, Fever And Headache.;Comparison Of fetal Complications (Heart Rate And Meconium Excretion) In Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) in Qazvin. Timepoint: Admision in Labure. Method of measurement: Number Of Meconium Excretion, Fetal Death, Apgar Score In First And Fifth Minutes, And Need For NICU Neonates due to Low Apgar Score.;Comparison Of Neonatal Outcom	—

Measure

Time frame

Comparison Of The InitiationI Induction Interval And The Time Of Onset Of Pain In The Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) In Qazvin. Timepoint: Admision in Labure. Method of measurement: Time.;Comparison Of The Duration Of Induction To Delivery In Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) In Qazvin. Timepoint: Admision in Labure. Method of measurement: Time.;3) Comparison Of Delivery Type In Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) In Qazvin. Timepoint: Admision in Labure. Method of measurement: NVD , C/S.;Comparison Of The Complications Of Clinical And Uterine Medication In Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) In Qazvin. Timepoint: Admision in Labure. Method of measurement: Tachycardia (presence Of 5 Or More Uterine Contractions In 10 minutes), Excessive Uterine Stimulation (Any Condition That Causes Abnormal Fetal Heart Rate), Uterine Hypertonia (Any Uterine Contraction Lasting More Than Two Minutes), Start Time Suitable Contractions Of Uterus, Interval Between Initiation Of Induction And Delivery, Type Of Delivery, Meconium Excretion, Fetal Death, Apgar Score In the First And Fifth Minutes, And The Need For NICU Neonates Due To Low Apgar Score And Side Effects Of The Drug. Digestive Complications Include Nausea, Vomiting, Diarrhea, Fever And Headache.;Comparison Of fetal Complications (Heart Rate And Meconium Excretion) In Three Groups Of Pregnant Mothers (Vaginal, Cervical, Sublingual) Referring To Maternity Hospitals (Mehregan, Kosar) in Qazvin. Timepoint: Admision in Labure. Method of measurement: Number Of Meconium Excretion, Fetal Death, Apgar Score In First And Fifth Minutes, And Need For NICU Neonates due to Low Apgar Score.;Comparison Of Neonatal Outcom

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahtab Dadashaliha

Qazvin University of Medical Sciences

dadashaliham@yahoo.com+98 28 3322 9304

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 14, 2026